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KMID : 1132720140120020076
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Genomics & Informatics
2014 Volume.12 No. 2 p.76 ~ p.78
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SFannotation: A Simple and Fast Protein Function Annotation System
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Yu Dong-Su
Kim Byung-Kwon
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Abstract
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Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a functional annotation system that uses extant databases, but the expansive size of these databases often causes a bottleneck for rapid functional annotation. We developed SFannotation, a simple and fast functional annotation system that rapidly annotates putative proteins against four extant databases, Swiss-Prot, TIGRFAMs, Pfam, and the non-redundant sequence database, by using a best-hit approach with BLASTP and HMMSEARCH.
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KEYWORD
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bioinformatics, gene product, protein annotation
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